Senior Associate Scientist - Analytical Development
Core
Developing and validating analytical methods for proteins, nucleic acids, and lipids to support cell line, upstream, and downstream development, and transferring them to QC for validation.
Role type
Senior Associate Scientist - Analytical Development
Builds
Analytical methods and reference standards for mRNA proteins and monoclonal antibodies (mAbs)
Domain
Biopharmaceuticals / Analytical Chemistry
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Biochemical/biophysical and immunological concepts, SDS-PAGE/Agarose Gel analysis, ELISA, Western Blot, HPLC, Capillary Electrophoresis (CE), cIEF, product binding/activity assays, qPCR, Sanger Sequencing, LCMS peptide mapping, intact mass analysis, released N-glycan analysis, experimental design (DoE), Analytical Quality by Design (AQbD), GMP documentation, Good Documentation Practices (GDP)
Preferred skills
LCMS peptide mapping, intact mass analysis, released N-glycan analysis
Technologies
SDS-PAGE, Agarose Gel, ELISA, Western Blot, HPLC, CE, cIEF, qPCR, Sanger Sequencing, LCMS
Responsibilities
Execute analysis of proteins and biological macromolecules from mammalian cell culture, develop robust assays using DoE and AQbD, record and verify experimental data, support sample shipments to clients, maintain project timelines, perform lab housekeeping and sterilization, write procedural SOPs, mentor or train others
Seniority
Senior, hands-on IC
