Principal Scientist Chemistry, Small Molecule Process Development and Manufacturing
Core
Lead and mentor teams to design, optimize, and characterize robust manufacturing processes for small molecule drug candidates from early to late phase development.
Role type
Principal Scientist, Chemistry (Process Development & Manufacturing)
Builds
Clinical and commercial therapeutics supply chain
Domain
Pharmaceutical/Biotech, Small Molecule Process Chemistry
Required skills
Route scouting, mechanistic experiments, process characterization, process safety, tech transfer protocols, API isolation, CDMO management, analytical tools, purification techniques
Preferred skills
Experience with piloting and manufacturing across modalities, familiarity with solid form and separations
Technologies
Laboratory instrumentation, analytical tools, purification techniques
Responsibilities
Design and conduct laboratory experiments to optimize and characterize processes; Lead experimental planning to advance the drug portfolio; Mentor less experienced staff; Develop fundamental process knowledge for scale-up; Collaborate with cross-functional teams for regulatory filings; Author CMC sections of INDs; Interact with CDMOs; Initiate innovative research projects; Represent the company externally.
Seniority
Principal, Management level with hands-on leadership
