Associate Scientific Director, Pharmacometrics
Core
Provide pharmacometrics expertise and advanced modeling/simulation to support quantitative decision-making for high-priority clinical development programs.
Role type
Associate Scientific Director, Pharmacometrics (Management level)
Builds
Supports drug development lifecycle activities including dose selection, regimen optimization, and clinical trial design.
Domain
Biopharmaceuticals / Pharmacometrics / Model Informed Drug Development (MIDD)
Deliverable
production ML models | dashboards & analysis
Required skills
Population PK/PD analysis, exposure-response analysis, clinical pharmacology principles, regulatory expectations for pharmacometrics, quantitative result interpretation, pharmacometrics software (NONMEM, Monolix, R), mechanistic/systems pharmacology modeling
Preferred skills
Mechanistic or systems pharmacology models
Technologies
NONMEM, Monolix, R
Responsibilities
Execute advanced pharmacometrics analyses (PK/PD modeling, simulation, exposure-response), identify opportunities to advance understanding of PK/PD/efficacy/safety via modeling, contribute to MIDD activities, communicate analysis results to program teams, mentor colleagues on methodologies, author pharmacometrics sections of clinical/regulatory documents, publish in scientific journals and present at events
Seniority
Management, Associate Director
