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Molecular & Cell Biology Senior Research Scientist

Boston, MA, US💼 Full-time💰 $121,600–$121,600🗓 2026-09-25 → 2026-09-26

Core

Develop, characterize, and apply physiologically relevant human neuronal cellular models using stem cells and primary cells to support disease biology understanding and novel drug discovery programs.

Role type

Senior IC molecular & cell biology research scientist (neuronal model development)

Builds

Human neuronal models (iPSC-derived, primary cells, 3D cultures) and scalable cell-based assays for therapeutic discovery

Domain

Biotechnology / Neuroscience / Stem Cell Biology

Deliverable

production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work

Required skills

iPSC reprogramming and differentiation, neuronal lineage generation, primary cell culture, laboratory automation operation, molecular biology techniques, genome editing, experimental design, data interpretation

Preferred skills

3D culture systems, organoids, high-content imaging, multi-omic data integration, Python/R/GraphPad Prism

Technologies

CRISPR/Cas9, RNA interference, Echo liquid handlers, Hamilton systems, bioreactors, FlowJo, ELISA, immunofluorescence

Responsibilities

Design and execute cellular and molecular biology studies for predictive disease modeling; Lead end-to-end iPSC model development from reprogramming to assay readiness; Operate and optimize automated laboratory platforms; Apply genome-editing and gene-modulation approaches to investigate disease mechanisms; Interpret complex experimental data and integrate findings with genomic and computational datasets

Seniority

Senior, hands-on IC

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