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Analytical Science and Technology Principal Scientist

Boston, MA💼 Full-time💰 $138,400–$138,400🗓 2026-09-11 → 2026-09-25

Core

Lead microbiology method lifecycle management, microbial control strategies, and technical oversight for biologics, cell therapy, and gene therapy products in late-stage development and commercialization.

Role type

Principal Scientist (Microbiology)

Builds

Robust, inspection-ready microbiological testing and control strategies for global biologics and cell/gene therapy programs.

Domain

Biopharmaceuticals / Microbiology / Biologics & Cell & Gene Therapy

Deliverable

production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work

Required skills

Microbiology method development and validation, Sterility testing, Bioburden testing, Endotoxin testing, Microbial identification, Rapid microbiological methods, GxP compliance, Investigation leadership, CAPA management, Contract laboratory oversight, Regulatory submission support

Preferred skills

Biologics lifecycle management, Cell and gene therapy experience, Commercial manufacturing support, Health authority interaction

Technologies

None explicitly listed

Responsibilities

Lead microbiology method qualification, validation, transfer, and lifecycle management; Develop risk-based microbial control strategies; Lead complex investigations and root cause analyses; Oversee testing at contract laboratories and CMOs; Support regulatory submissions and inspection readiness; Provide technical leadership and mentoring to scientists

Seniority

Principal, hands-on IC with strategic oversight

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