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Senior Principal Scientist, Translational Profiling Imaging

Cambridge (USA)💼 Full-time💰 $138,600–$138,600🗓 2026-09-24 → 2026-09-26

Core

Lead a small group of biologists with advanced imaging expertise to drive integration of spatial proteomics and imaging technologies for complex target discovery and validation across disease areas.

Role type

Senior Principal Scientist / Associate Director (hands-on IC with matrix leadership)

Builds

Novel assays, integrated workflows, and biological insights for drug discovery

Domain

Biomedical Research / Drug Discovery / Advanced Imaging / Spatial Biology

Deliverable

production ML models | product features | dashboards & analysis | research

Required skills

Experimental biology, cellular and tissue-based models, confocal microscopy, super resolution microscopy, assay development, data interpretation, scientific leadership, mentoring, cross-functional collaboration, emerging technology evaluation

Preferred skills

Multi-omics integration, target and drug discovery experience in industry, AI-enabled approaches for imaging and data analysis

Technologies

Confocal microscopy, super resolution microscopy, spatial biology platforms, proteomics, metabolomics, lipidomics, AI-enabled imaging tools

Responsibilities

Lead development of translational biology and imaging strategies; Design and implement novel assays and integrated workflows; Maintain active hands-on presence in experimental design and troubleshooting; Generate biological insights into disease mechanisms and pharmacology; Lead cross-functional matrix teams; Shape strategy for imaging and spatial biology capabilities; Establish external collaborations for emerging technologies; Mentor scientists and communicate findings to stakeholders

Seniority

Senior Principal Scientist / Associate Director, hands-on IC with strategic leadership

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