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Research Scientist I or II, Oligonucleotide Chemistry

Cambridge (USA)💼 Full-time💰 $66,800–$66,800🗓 2026-08-13 → 2026-09-26

Core

Synthesize, optimize, and characterize therapeutic oligonucleotides using automated solid-phase synthesis and analytical techniques to advance RNA-based medicines.

Role type

Research Scientist (Oligonucleotide Chemistry)

Builds

Research-scale oligonucleotides for xRNA therapeutics discovery

Domain

Biopharmaceuticals / RNA therapeutics / Oligonucleotide Chemistry

Deliverable

production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work

Required skills

Automated solid-phase synthesis, chromatography, mass spectrometry, oligonucleotide purification, RNA therapeutics knowledge, laboratory instrumentation operation, SOP development

Preferred skills

Oligonucleotide process development, technology innovation

Technologies

Automated DNA/RNA synthesizers, chromatographic systems, mass spectrometry

Responsibilities

Execute solid-phase synthesis of research-scale oligonucleotides; Purify, desalt, and characterize oligonucleotides; Develop and optimize synthesis and analytical methods; Operate and maintain laboratory instrumentation; Prepare and maintain standard operating procedures; Organize and document experimental results

Seniority

Mid-level, hands-on IC

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