Research Scientist I or II, Oligonucleotide Chemistry
Core
Synthesize, optimize, and characterize therapeutic oligonucleotides using automated solid-phase synthesizers and analytical techniques to advance RNA-based medicines.
Role type
Research Scientist I or II, Oligonucleotide Chemistry
Builds
Research-scale oligonucleotides for xRNA therapeutics discovery
Domain
Biopharmaceuticals / RNA therapeutics / Oligonucleotide Chemistry
Required skills
Automated solid-phase synthesis, Oligonucleotide purification, Chromatography, Mass spectrometry, Laboratory instrumentation operation, SOP development, Electronic laboratory notebook management
Preferred skills
Oligonucleotide process development, Technology innovation
Technologies
Automated DNA/RNA synthesizers, Chromatographic systems, Mass spectrometry systems
Responsibilities
Execute solid-phase synthesis of research-scale oligonucleotides; Purify, desalt, and characterize oligonucleotides; Develop and optimize synthesis and analytical methods; Operate and maintain laboratory instrumentation; Prepare and maintain standard operating procedures; Organize and document experimental results
Seniority
Mid-level Research Scientist (1-3 years experience)
