Principal Scientist II, Translational Biomarker Strategy Lead
Core
Lead development of preclinical and translational biomarker strategies for drug discovery programs from target validation through early clinical development readiness.
Role type
Principal Scientist II, Translational Biomarker Strategy Lead
Builds
Execution-ready biomarker plans enabling efficient progression of the portfolio
Domain
Pharmaceutical/Biotechnology, Translational Medicine, Drug Development
Required skills
Translational research, Biomarker strategy, Drug development, Cross-functional matrix leadership, Stakeholder management, Target engagement, Pharmacodynamics, Patient stratification, Mechanism-based biomarkers
Preferred skills
Chemical Biology, Gene Therapy, Machine Learning (ML), Python (Programming Language), Clinical Trials, Molecular Biology, Immunology
Technologies
Python, Machine Learning (ML)
Responsibilities
Lead development of stage-appropriate preclinical and translational biomarker strategies; Define biomarker hypotheses, context of use, evidence requirements, and decision criteria; Develop integrated biomarker plans encompassing assays, models, samples, analyses, timelines, and external partnerships; Drive external collaborations and leverage innovative technologies, datasets, and human sample resources; Generate translational evidence linking target biology, pharmacology, and biomarkers to support key portfolio decisions.
Seniority
Principal, strategy & mentorship
