Principal Scientist - Formulation
Core
Lead formulation development and characterization strategies for complex biologics including monoclonal antibodies, multispecifics, and antibody-drug conjugates during early-stage development.
Role type
Principal Scientist (Formulation)
Builds
Stable formulations and clinical candidates for biotherapeutic modalities
Domain
Biopharmaceuticals / Biologics
Required skills
Protein formulation, Biophysical property assessment, Preformulation study design, Stability-indicating assay interpretation, Team leadership, Analytical instrumentation operation
Preferred skills
Viral vector gene therapy formulation, Design of Experiments (DoE), Automated liquid handling
Technologies
DSC, DLS, UV-Vis, SEC, CE, MS, JMP, Python
Responsibilities
Design and execute formulation screening strategies, Lead studies to identify stable formulations, Manage team resources and timelines, Provide leadership and mentorship to team members, Partner with CMC teams to advance clinical candidates, Develop stabilization strategies for various drug product formats
Seniority
Principal, hands-on IC with team leadership
