Senior Associate Scientist - Proteogenomics & Immunopeptidomics

TARRYTOWN, USFull-time2026-11-06 → 2026-11-10

Core

Hands-on laboratory role discovering and validating novel cell-surface and HLA-presented antigens for therapeutic antibody, bispecific, and cell-therapy programs using mass spectrometry.

Role type

Senior Associate Scientist (Proteogenomics & Immunopeptidomics)

Builds

Validated target candidates for discovery teams

Domain

Biotechnology / Proteomics / Immunopeptidomics

Required skills

Mass spectrometry operation, LC-MS/MS data acquisition, immunoprecipitation, bottom-up proteomics sample preparation, database searching, false-discovery control, Python/R scripting, data analysis

Preferred skills

LC-MS experience, protein biochemistry, immunology background, machine learning interest

Technologies

Thermo Orbitrap, Bruker timsTOF, Python, R, PEAKS, FragPipe, Proteome Discoverer, Spectronaut

Responsibilities

Perform bottom-up proteomics sample preparation, carry out immunoprecipitation workflows, acquire LC-MS/MS data, maintain instrument calibration and troubleshooting, process MS data through database search workflows, review and filter results, build custom protein sequence databases, present data at group meetings

Seniority

Senior, hands-on IC

About Regeneron

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regu