Scientist, Analytical and Biological Mass Spectrometry (ABMS)
Core
Develop and optimize LC-MS-based analytical methods and analyze data to characterize the quality attributes of therapeutic proteins, antibodies, and emerging modalities for R&D programs.
Role type
Senior Scientist, Analytical and Biological Mass Spectrometry
Builds
Biochemical characterization data for emerging therapeutic modalities and monoclonal antibodies
Domain
Biopharmaceuticals / Analytical Chemistry
Required skills
LC-MS method development, LC-MS data analysis, sample preparation for biological matrices, metabolomics, lipidomics, experimental design, statistical analysis, SOP development, regulatory document preparation
Preferred skills
Metabolic flux analysis, isotope tracing, pharmaceutical formulation, process development, AAV virology, siRNA, structural biology, automated liquid-handling systems, HDX-MS, IMS-MS, quantitative proteomics
Technologies
LC-MS, ELN, Biomek, Bravo, KingFisher, Tecan, DoE software, molecular modeling tools
Responsibilities
Develop and optimize LC-MS-based analytical methods; Analyze and interpret LC-MS data to characterize therapeutic proteins; Perform sample preparation and LC-MS experiments according to SOPs; Present data at meetings and prepare technical reports and regulatory documents; Summarize results using graphs and tables for publications and regulatory submissions; Document experiments and results in electronic laboratory notebooks.
Seniority
Senior, hands-on IC
