Senior Medical Director, Clinical Development, MASH
Core
Lead MASH (Metabolic and Associated Syndromes) clinical programs from first-in-human through registration-enabling studies for genetic medicines.
Role type
Senior Medical Director, Clinical Development
Builds
Genetic medicines for metabolic diseases using modalities like RNAi, gene editing, and viral vectors
Domain
Biotechnology / Genetic Medicine / Metabolic Diseases
Required skills
Clinical trial leadership, Regulatory strategy, Cross-functional team management, Patient safety oversight, Clinical document quality, Target evaluation
Preferred skills
MASH domain experience, Academic research experience
Technologies
RNAi, Gene editing, Viral vectors
Responsibilities
Lead MASH clinical programs and serve as clinical expert with regulators and advisory boards; Design and execute Phase 1-3 studies; Develop clinical strategies to shorten development timelines; Partner with scientists to evaluate genetic medicine targets; Safeguard patient safety and review post-marketing signals; Ensure quality of clinical documents and prepare regulatory submissions; Build consensus across multi-disciplinary teams.
Seniority
Senior, hands-on IC
