Scientist, Cardiac Vascular - In Vivo
Core
Perform advanced surgical models of cardiac and vascular disease in rodents to support cardiovascular therapeutic development.
Role type
Senior IC preclinical surgical scientist (cardiovascular)
Builds
Preclinical in-vivo rodent studies for target validation and therapeutic development
Domain
Biopharma / Cardiovascular research
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Rodent cardiac and vascular surgical models (TAC, MI, RKM), Telemetry implantation, Invasive hemodynamic measurement (PV-loop), Langendorff perfusion, Cardiac tissue dissociation, Data analysis software (PRISM, PONEMAH), Animal welfare compliance
Preferred skills
Additional cardiovascular functional assessment techniques, GLP/regulated research environment experience
Responsibilities
Perform surgical models of cardiac and vascular disease, Administer test articles via multiple routes, Implant and manage telemetry devices, Conduct invasive hemodynamic assessments, Perform ex-vivo tissue collection and processing, Manage end-to-end in-vivo study logistics, Analyze and interpret physiological and functional data, Generate high-quality figures and reports for regulatory and publication use
Seniority
Senior, hands-on IC