Principal Scientist (Scientific Director Level)– Nonclinical Drug Safety
Core
Lead nonclinical drug safety strategy for discovery programs in immunology and oncology, defining risk assessments and de-risking strategies from target identification to First-In-Human enabling studies.
Role type
Principal Scientist (Scientific Director Level) – Nonclinical Drug Safety
Builds
Novel medicines for patients, supporting selection of therapeutic candidates and regulatory documents for clinical trials.
Domain
Biopharmaceuticals, Nonclinical Drug Safety, Immunology, Oncology
Required skills
Nonclinical safety strategy, Risk assessment, GLP toxicology study execution, Cross-functional matrix management, Therapeutic area discovery governance, Regulatory submissions, Toxicology, Pathology
Preferred skills
Biopharmaceutical development, Small molecule development, Regulatory responses, Pharmaceutical consortia membership
Technologies
GLP, FIA (First-In-Human), ADC, Small molecules, Peptides, Biologics
Responsibilities
Represent NDS on discovery teams and participate in therapeutic area governance reviews; Promote creative thinking from target identification through lead optimization; Identify and assess potential risks associated with therapeutic targets using literature and internal data; Lead early development teams to inform preclinical studies; Define GLP toxicology study strategy and execution for development teams.
Seniority
Principal, strategy & mentorship
