CareerPlanGet AI match score →

Principal Scientist, Systems and Disease Biology

Cambridge, MA💼 Full-time💰 $122,250–$122,250🗓 2026-07-10 → 2026-07-31

Core

Decoding disease mechanisms at cellular resolution and pioneering AI-powered workflows to accelerate discovery from target identification to patient impact.

Role type

Principal Scientist, Systems and Disease Biology

Builds

First-in-class medicines for immunology, neurology, and oncology

Domain

Biopharma / Systems Biology / AI in Drug Discovery

Deliverable

production ML models | research

Required skills

Multi-omics and multimodal data analysis, ML/AI and agentic workflow development, complex cellular analytics, project leadership, scientific communication

Preferred skills

Experience in organoid or CRISPR assays, track record of publications or patents

Technologies

Multi-omics platforms, agentic analysis workflows, computational models

Responsibilities

Generate hypotheses on disease drivers by integrating multi-omics and clinical metadata; Design intelligent agentic workflows for algorithm deployment; Lead projects involving internal experiment design and outsourcing of mechanistic assays; Collaborate on method development and disease-focused studies; Lead high-profile presentations and publications; Mentor interns and junior scientists

Seniority

Principal, hands-on IC with mentorship

Sourced via workday · Listed on CareerPlan, which tracks 70,000+ jobs from 20+ sources.
Apply on Workday ↗