R&D - TMU - Clinical Lead, Early Clinical & Experimental Therapeutics - SH
Core
Design and lead early clinical development of oncology assets (small molecules, mAbs, ADCs, immune cell engagers) for solid tumors and hematologic malignancies in China, focusing on First-In-Human studies, Proof-of-Mechanism, and natural history studies.
Role type
Senior Clinical Lead, Early Clinical & Experimental Therapeutics (Oncology)
Builds
Early clinical development plans and First-In-Human studies for novel oncology therapeutics
Domain
Oncology, Early Clinical Development, Translational Medicine
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Design and execution of early development clinical trials (Phase 1a/b, 2a), leading cross-functional teams, CRO management, Medical Safety oversight, Translational/biomarker research, Emerging digital/AI-driven tools
Preferred skills
Global pharma setting experience, Late phase clinical trials conduct
Technologies
Emerging digital/AI-driven tools
Responsibilities
Design safe and rapid First-In-Human studies, Make front-line decisions on protocol design and dose escalation, Supervise execution of clinical studies, Review and interpret results to author clinical documentation, Coordinate oversight of CROs and cross-functional teams, Ensure Clinical Trial standards are maintained
Seniority
Senior, hands-on IC
