Principal Research Associate, Clinical Biomarker Laboratory, Flow Cytometry
Core
Technical expert in clinical immunology generating high-parameter flow cytometry data to inform clinical development decisions for mRNA therapeutics.
Role type
Principal Research Associate (Clinical Biomarker Laboratory)
Builds
Clinical trial data via high-parameter spectral flow cytometry assays for multiple therapeutic areas
Domain
Biopharma / Clinical Immunology / Spectral Flow Cytometry
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Spectral flow cytometry, PBMC isolation and cryopreservation, ex vivo stimulation protocols, immunophenotyping, GCLP compliance, FCS Express, Cytek Aurora operation, assay development, data analysis, SOP creation
Preferred skills
Cell culture, intracellular cytokine staining, GraphPad Prism, R, computational skills, regulated environment experience (GCP/GLP/ISO)
Technologies
Cytek Aurora, BD Fortessa/Symphony, FCS Express, OMIQ, FlowJo, ELN, LIMS
Responsibilities
Execute clinical sample testing under GCLP, perform high-parameter immunophenotyping on PBMC/whole blood, develop and validate spectral flow cytometry assays, analyze complex datasets, act as study/assay lead when assigned, mentor junior team members, support regulatory documentation
Seniority
Senior, hands-on IC with mentorship responsibilities
