Research Associate - MiND iPSC & Screening Platform
Core
Culturing, reprogramming, and differentiating patient-derived human iPSCs to study neurodegenerative disease phenotypes and mechanisms using high-content imaging and AI-based analysis.
Role type
Research Associate (iPSC & Screening Platform)
Builds
iPSC-based disease models and high-content imaging phenotypic screens
Domain
Biomedical research / Neurodegenerative diseases / Stem cell biology
Deliverable
production ML models | product features | dashboards & analysis | research
Required skills
Human iPSC culture and maintenance, Reprogramming, Differentiation, Sterile technique, Molecular cloning, Western blotting, Immunofluorescence, Confocal microscopy, Image analysis, CRISPR-Cas9 gene editing, Small molecule screening
Preferred skills
AI/machine learning software for phenotype quantification, Lab database management
Technologies
CRISPR-Cas9, Confocal microscopy, AI/machine learning-based software
Responsibilities
Culturing, reprogramming, differentiating, and maintaining human iPSCs under sterile conditions; Characterizing human iPSC cultures using biochemical analysis, molecular cloning, plasmid preparation, Western blotting, immunofluorescence, and confocal microscopy; Designing and performing phenotypic screens using gene-editing technology and small molecule libraries; Using AI/machine learning-based software to characterize and quantify disease phenotypes in iPSC-based models; Training researchers on iPSC maintenance and differentiation; Upkeeping laboratory equipment and lab databases
Seniority
Mid-level, hands-on IC
