Principal Scientist, Discovery BioSciences – Integrative New Targets, Oncology
Core
Lead efforts at the intersection of agentic AI, machine learning, functional genomics, and target discovery to identify and validate new oncology therapeutic targets.
Role type
Principal Scientist (AI/ML & Cancer Biology)
Builds
Novel oncology therapeutic targets and actionable insights for drug development.
Domain
Oncology, Drug Discovery, AI/ML, Functional Genomics
Deliverable
production ML models
Required skills
Cancer biology, AI/ML, functional genomics, single cell and spatial 'omics, genomics and proteomics data analysis, target identification strategies (forward/reverse genetic screens, CRISPR, molecular biology), mechanistic biology understanding, statistical modeling
Preferred skills
Computational biology, systems biology, antibody-drug conjugates, T-cell engagers, multispecifics, radioligand therapies, scientific publication history
Technologies
agentic AI, foundation models, genome engineering techniques, CRISPR, degron tagging
Responsibilities
Develop and pressure test applied data science methodologies to identify new targets; Co-develop and execute multi-disciplinary research strategies for target identification; Collaborate on innovative machine learning algorithms and AI platforms; Play a leading role in matrix teams for new leads, computational chemistry, and spatial technologies
Seniority
Principal, hands-on IC with strategy
