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Principal Scientist, AI-Driven Oncology Target Discovery

Cambridge Crossing - MA - US💼 Full-time💰 $166,770–$166,770🗓 2026-06-04 → 2026-07-31

Core

Drive identification of novel therapeutic targets and resistance mechanisms in oncology by integrating multimodal biological, clinical, and real-world datasets to generate actionable insights for target nomination and portfolio strategy.

Role type

Principal Computational Scientist (AI/ML)

Builds

Agentic AI and machine learning systems for scalable, end-to-end target discovery workflows

Domain

Oncology drug discovery, computational biology, machine learning

Deliverable

production ML models

Required skills

Machine learning, agentic AI, multimodal data integration, functional genomics, systems biology, target identification, scientific reporting, cross-functional leadership

Preferred skills

Ph.D. in computational biology or related quantitative field, single-cell and spatial omics expertise, LLM-driven application development, oncology disease biology, publication record in computational biology

Technologies

Agentic AI frameworks, LLMs, omics data platforms, real-world data analytics tools

Responsibilities

Drive integration of computational approaches into cross-functional target discovery workflows; Lead design and deployment of agentic AI and ML systems; Integrate and analyze multimodal patient-derived datasets; Translate analytical outputs into decision-ready insights for Go/No-Go recommendations; Author scientific reports and present methods to publishable standards

Seniority

Principal, hands-on IC with strategic influence

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