Principal Scientist, Pharmaceutical Development
Core
Principal Scientist leading pharmaceutical development and developability science to mitigate risks and accelerate drug candidates from discovery to development using experimental, computational, and AI-enabled approaches.
Role type
Principal Scientist, Pharmaceutical Development (Drug Discovery)
Builds
Drug candidates progressing from discovery into development for global pharmaceutical and biotechnology clients
Domain
Pharmaceutical Sciences / Drug Delivery / Developability Science
Required skills
Developability science, Drug delivery, Physicochemical sciences, Biopharmaceutics, Solid-state science, AI-enabled approaches, Experimental design, Computational modeling, Project leadership, Client engagement
Preferred skills
Model-informed formulation design, PK data interpretation, Mechanistic developability modeling (DCS, PBPK), Solubility/dissolution/absorption risk evaluation, Non-oral dosage route expertise, Beyond Rule of 5 compounds
Technologies
DCS, PBPK, AI-enabled platforms, Computational modeling frameworks
Responsibilities
Design and oversee developability studies, Integrate physicochemical and formulation data, Apply AI and computational approaches for risk assessment, Translate insights into recommendations for drug discovery teams, Recommend formulation strategies for challenging molecules, Lead pharmaceutical development projects from proposal to delivery, Act as primary scientific contact for clients, Mentor junior scientists
Seniority
Principal, scientific leadership & mentorship
