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Principal Enterprise Architect - AI & Agents (Remote)

2 Locations🌐 Remote💼 Full-time💰 $118,100–$118,100🗓 2026-07-06 → 2026-07-31

Core

Define, govern, and evolve enterprise architecture strategy, standards, and roadmaps for AI and agentic solutions across a global technology landscape.

Role type

Principal Enterprise Architect (AI & Agentic Solutions)

Builds

Enterprise reference architectures, standards, reusable patterns, and capability models for AI and agentic systems.

Domain

Life sciences / Healthcare / Enterprise Architecture / Generative AI

Deliverable

production ML models

Required skills

Enterprise architecture strategy, generative AI concepts, agentic systems design, vector databases, RAG, tool-use, MCP servers, HITL, evaluation frameworks, observability, cloud architecture (Azure/AWS), modern data architectures, API-first integration, event-driven architecture, microservices, stakeholder management, business case building

Preferred skills

Healthcare/life sciences domain knowledge, clinical trial lifecycle, real-world evidence, EMR ecosystems, enterprise architecture tools (LeanIX, Ardoq, MEGA), capability modeling methodologies

Technologies

Azure, AWS, LangGraph, LeanIX, Ardoq, MEGA

Responsibilities

Define and maintain enterprise reference architectures and standards for generative AI; Govern solution designs and technical component selection; Provide architectural oversight for major AI initiatives; Translate business strategies into capability-based roadmaps; Drive enterprise interoperability and integration patterns; Partner with compliance and security teams on regulatory alignment; Maintain enterprise capability models and architecture artifacts; Identify platform consolidation opportunities; Guide senior stakeholders on architectural trade-offs; Mentor architects and senior engineers.

Seniority

Principal, strategy & mentorship

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