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Principal Knowledge & Data Architect

Headquarters💼 Full-time💰 $174,770–$174,770🗓 2026-07-07 → 2026-07-31

Core

Design and operate the knowledge management layer for AI, turning institutional information into structured, retrievable knowledge for retrieval-augmented generation (RAG) pipelines and knowledge graphs.

Role type

Principal Knowledge & Data Architect

Builds

RAG pipelines, knowledge graphs, and entity resolution systems for HHMI's administrative and operational functions.

Domain

Biomedical research institutions / Generative AI / Knowledge Engineering

Deliverable

production ML models

Required skills

Production RAG systems, Knowledge graph design and operation, Entity resolution and deduplication, Information extraction (LLM/NLP/Rule-based), Data modeling and classification, Python, SQL, Vector databases, Graph databases

Preferred skills

Hybrid retrieval and GraphRAG patterns, Master data management, Semantic web technologies (RDFS, OWL, SKOS), AI agent tool design

Technologies

Python, SQL, Postgres pgvector, Pinecone, Weaviate, Qdrant, Neo4j, AWS Neptune, JanusGraph, TigerGraph, Stardog, Cypher, SPARQL, Gremlin, Databricks, dbt

Responsibilities

Design knowledge representation strategies (chunking, embeddings, graphs), build and operate RAG pipelines, construct knowledge graphs for complex reasoning, extract structure from unstructured documents, solve entity resolution and canonicalization, govern knowledge classification and lineage, partner with data integrations and AI platform teams

Seniority

Principal, hands-on IC with strategy & mentorship

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