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Director, Translational AI & Mechanistic Biology

UK - Cambridge💼 Full-time🗓 2026-09-15 → 2026-09-26

Core

Director leading Translational AI to uncover biological mechanisms driving disease, treatment response, and resistance by integrating multimodal data (omics, imaging, clinical) and applying advanced AI to accelerate drug development.

Role type

Director, Translational AI & Mechanistic Biology

Builds

Reusable AI methods, platforms, and capabilities for translational science and drug development

Domain

Biopharmaceutical R&D, Computational Biology, Translational Medicine

Deliverable

production ML models

Required skills

Foundation model training and fine-tuning, model interpretability and explainability, causal machine learning, graph machine learning, agentic AI, Python, deep learning frameworks (PyTorch), cloud platforms (AWS/Azure/GCP), generating novel insights from complex biological datasets

Preferred skills

Human disease biology, translational datasets (genomics, transcriptomics, proteomics, single-cell, spatial biology, pathology imaging, longitudinal/real-world data), pharmaceutical research lifecycle, mechanism of action studies, biomarker discovery, patient stratification, systems biology, biomedical knowledge graphs

Technologies

PyTorch, AWS, Azure, GCP, LLM tooling, frontier coding agent frameworks

Responsibilities

Apply AI to elucidate disease mechanisms and drug mechanisms of action; Integrate molecular, cellular, omics, imaging, and clinical data to generate biological insights; Develop models connecting targets, pathways, biomarkers, and clinical outcomes; Build analytical frameworks deployable across multiple therapeutic areas; Partner with translational scientists, clinicians, and bioinformaticians; Mentor junior scientists and contribute to best practices

Seniority

Director, strategy & mentorship

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