Associate Principal Scientist II – LVV Characterization
Core
Design, execute, and analyze in vitro characterization studies for lentiviral vectors (LVV) to assess critical quality attributes including identity, titer, infectivity, purity, and stability.
Role type
Associate Principal Scientist II (Analytical Development)
Builds
Analytical methods and data supporting LVV product quality and process development
Domain
Biopharmaceuticals / Gene Therapy / Viral Vectors
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
in vitro LVV characterization, analytical method development, qPCR/dPCR/RT-qPCR, flow cytometry, ELISA, Western blot, statistical analysis, technical writing
Preferred skills
experience with lentiviral vectors, gene therapy products, regulated environment laboratory work
Technologies
qPCR, dPCR, RT-qPCR, flow cytometry, ELISA, Western blot, immunofluorescence
Responsibilities
Design and execute in vitro characterization studies; develop and optimize analytical assays for viral vectors; support investigation of critical quality attributes and process parameters; lead analytical method validation and technology transfer; perform statistical analysis of experimental data; prepare technical documentation and study reports; collaborate cross-functionally with process development and quality teams; manage interactions with external CROs and laboratories.
Seniority
Senior, hands-on IC