Associate Principal Scientist - Process Analytical Technology (PAT) and Chemometrics
Core
Expert support for continuous manufacturing of commercial pharmaceutical products using Process Analytical Technology (PAT) and chemometrics.
Role type
Associate Principal Scientist (Process Analytical Technology and Chemometrics)
Builds
Robust PAT/model control strategies and multivariate models for on-market drug products.
Domain
Pharmaceutical manufacturing / Chemometrics / Spectroscopy
Deliverable
production ML models
Required skills
Chemometrics, Multivariate Data Analysis (MVDA), Machine Learning, PAT orchestration (SIPAT/SynTQ), NIR/Raman/Microwave resonance spectroscopy, Multivariate Statistical Process Control (MSPC), Technology Transfer, Business strategy definition, Scientific leadership, Vendor management, Data analytics
Preferred skills
Digital Twins, Simulation models, Lean problem-solving, Separation science, NMR, Mass spectrometry
Technologies
SIMCA, Unscrambler, MATLAB
Responsibilities
Manage lifecycle of chemometric models for commercial supply; Implement PAT to develop process understanding and evolve control strategies; Resolve PAT instrument/model-related manufacturing issues using multivariate analysis; Define business strategy for PAT/MSPC integration; Lead stakeholder engagement for new PAT technologies; Support model updates, validation, and transfer to external partners.
Seniority
Senior, hands-on IC with strategic leadership
