Scientist - Rare Disease Biology
Core
Investigate disease mechanisms and evaluate therapeutic hypotheses for rare diseases, specifically Thyroid Eye Disease (TED), using experimental and data-driven approaches.
Role type
Scientist - Rare Disease Biology (Research IC)
Builds
Innovative therapies for rare diseases
Domain
Biotech / Rare Disease Biology / Fibro-inflammatory mechanisms
Deliverable
production ML models | product features | dashboards & analysis | research
Required skills
Experimental design and execution, in vitro/ex vivo study analysis, multi-omics data integration, human genetics interpretation, mechanistic insight generation, scientific literature synthesis, data-driven decision support
Preferred skills
Fibroblast biology expertise, tissue remodeling knowledge, primary human cell culture, organoid models, multi-omics data analysis, computational biology integration, AI-enabled scientific tools
Technologies
Multi-omics datasets, computational workflows, image analysis, automation tools
Responsibilities
Design and execute in vitro/ex vivo studies to investigate disease mechanisms; Generate reproducible experimental data for target validation; Integrate findings with human genetics, clinical observations, and omics data; Collaborate with multidisciplinary research teams; Communicate scientific findings to project teams and governance forums
Seniority
Mid-Senior, hands-on IC