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Senior Director, Process Development, RNA & Small Molecule Therapies

2 Locations💼 Full-time💰 $222,400–$222,400🗓 2026-06-12 → 2026-09-26

Core

Strategic and operational leader accountable for establishing and delivering robust, scalable, and compliant manufacturing processes for oligonucleotide therapeutics and siRNA modalities from early development through commercialization.

Role type

Senior Director, Process Development (RNA & Small Molecule Therapies)

Builds

Oligonucleotide therapeutics and siRNA modalities for patients with muscle, central nervous system, and cardiac diseases

Domain

Biopharmaceutical manufacturing, RNA therapeutics, GMP

Deliverable

production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work

Required skills

Process development strategy, scale-up, GMP manufacturing, tech transfer, regulatory interactions, QbD-aligned control strategies, CMC documentation, CDMO oversight, chemical linking strategies, process characterization

Preferred skills

Platform approach development, cross-functional collaboration, resolving investigations, monitoring performance

Technologies

Oligonucleotide therapeutics, siRNA modalities, GMP facilities

Responsibilities

Define and execute phase-appropriate process development strategies, lead teams covering process development and validation readiness, develop platform approaches to improve efficiency, provide technical oversight for performance monitoring and investigations, support CDMO selection and oversight, drive CMC documentation and regulatory submissions

Seniority

Senior Director, strategic & operational leadership

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