Senior Scientist or Scientist - Drug Metabolism and Pharmacokinetics (DMPK)
Core
Conducts laboratory-based DMPK studies (bioanalysis, in vitro assays, in vivo PK) to support small-molecule drug discovery and development.
Role type
Senior Scientist or Scientist, Drug Metabolism and Pharmacokinetics (DMPK)
Builds
Preclinical data supporting PK/PD, ADME, and efficacy evaluations for small-molecule drugs
Domain
Pharmaceutical research / Drug discovery
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
LC-MS/MS bioanalysis, in vitro DMPK assays (protein binding, microsomal stability, hepatocyte metabolism, permeability), in vivo PK study execution (dosing, sampling, tissue collection), preclinical formulation preparation
Preferred skills
Experience with SCIEX instrumentation
Technologies
LC-MS/MS, LIMS
Responsibilities
Perform quantitative LC-MS/MS bioanalysis of small/large molecules; Execute in vitro DMPK assays; Conduct in vivo PK studies; Develop preclinical formulations; Analyze data and maintain records; Communicate results to team
Seniority
Senior Scientist (10+ years) or Scientist (8+ years)
