CareerPlan

Staff Scientist

Chicago, IL, USFull-time$80k–$100k2026-10-19 → 2026-11-10

Core

Lead chemical biology efforts in a therapeutic core facility, driving early-stage drug discovery through experimental design, synthesis, and screening.

Role type

Senior IC medicinal chemist / chemical biologist

Builds

Therapeutic discovery pipeline via fragment-based drug discovery, lead optimization, and high-throughput screening

Domain

Academic research / Chemical biology / Medicinal chemistry

Required skills

organic synthesis, fragment-based drug discovery, high-throughput screening, lead optimization, assay development, PK/PD analysis, protein biochemistry

Preferred skills

drug design, library synthesis, molecular docking, protein expression and purification

Technologies

N/A

Responsibilities

Design and perform experiments in chemical synthesis, drug solubility, membrane permeability, and liver microsome stability; Collaborate with faculty, postdocs, and students to facilitate research programs; Provide technical expertise, mentorship, and training to junior researchers; Oversee research operations, equipment maintenance, and laboratory protocols; Develop laboratory protocols and training on new techniques; Manage, analyze, and make recommendations on complex data sets

Seniority

Senior, hands-on IC