Research Associate - Pouladi Lab
Core
Develop and analyze mouse and human pluripotent stem cell models of genetic neurological disorders, including preclinical therapeutic studies and brain development defect analysis.
Role type
Senior Research Associate (Neuroscience/Genetics)
Builds
Novel disease models, neural organoids, and preclinical therapeutic data
Domain
Academic research in medical genetics and neurobiology
Required skills
Mouse model research, Histology (immunofluorescence, IHC, ISH, TEM), Animal husbandry, Molecular biology (Western blot, PCR, cloning), Cell culture (organotypic slices, primary neurons), Human pluripotent stem cell differentiation, CRISPR/Cas9 genome editing, Electrophysiology (MEA)
Preferred skills
None stated
Technologies
CRISPR/Cas9, MEA, TEM, PCR
Responsibilities
Develop mouse and human pluripotent stem cell models of genetic neurological disorders; Analyze brain development defects in mouse models; Perform preclinical therapeutic studies; Conduct behavioral and histological analyses; Differentiate human pluripotent stem cells into neural cell types; Maintain and analyze cell line and brain slice cultures; Perform CRISPR-Cas9 genome editing and lentivirus infection; Conduct electrophysiological recordings
Seniority
Senior, hands-on IC