Principal Scientist
Core
Lead global client programs for bioanalytical testing of preclinical and clinical specimens using LC/MS/MS methods to advance clinical trials and innovative therapies.
Role type
Principal Scientist (Research Scientist) specializing in bioanalytical LC/MS/MS method development and validation.
Builds
Robust LC/MS/MS assays and validated methods for small molecules, radiolabeled compounds, and biologics (ADCs, oligonucleotides, mAb).
Domain
Clinical research / Bioanalytical chemistry / Pharmaceutical industry.
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
LC/MS/MS method development, method validation, assay strategy design, data interpretation, statistical analysis, project management, technical writing, cross-functional collaboration.
Preferred skills
Experience with new biological modalities, consulting with sponsors on assay requirements, publishing in peer-reviewed literature.
Technologies
Tomtec, Hamilton, Kingfisher, Integra Assist plus.
Responsibilities
Independently direct development and validation of new LC/MS/MS assays; ensure robust methods for small molecules, radiolabeled analytes, and biologics; review data presentations for accuracy; support Laboratory Operations with troubleshooting; provide technical input for marketing collateral; consult with sponsors on new project requirements; lead assay transfers to other lab locations.
Seniority
Principal, hands-on IC with strategic client program leadership.