Postdoctoral Fellow | Host-Microbiome Biology/ Organ-on-Chip Models | Jalili Lab
Core
Investigate how interactions between intestinal bacteria and patient-derived epithelial tissues shape cellular states, tissue function, and disease susceptibility, primarily using colorectal cancer as a model.
Role type
Postdoctoral Fellow (experimental scientist)
Builds
Patient-derived human colon organoids and perfused, hypoxia-enabled colon-on-a-chip models
Domain
Biomedical research, host-microbiome interactions, cancer biology, tissue engineering
Required skills
3D organoid culture, microphysiological systems operation, bacterial-epithelial coculture, microscopy, gene-expression analysis, quantitative functional assays
Preferred skills
Organ-on-a-chip technologies, microfluidics, gastrointestinal biology, transcriptomics, multi-omics approaches, in vivo models
Technologies
Microfluidics, microphysiological systems, transcriptomic approaches
Responsibilities
Establish and characterize patient-derived human intestinal organoids; Operate and optimize perfused, hypoxia-enabled gut-on-a-chip models; Design and conduct controlled bacterial-epithelial coculture experiments; Apply cellular and molecular techniques to investigate epithelial responses; Integrate functional studies with transcriptomic and molecular profiling approaches
Seniority
Postdoctoral Fellow