Meridial – Scientist – In Vivo Neurophysiology
Core
Develop and perform advanced in vivo experiments in mice combining intracellular electrophysiology, two-photon imaging, and optogenetic stimulation to map functional neural circuits.
Role type
Senior experimental neuroscientist (in vivo neurophysiology)
Builds
3D imaging and photostimulation technologies for functional mapping of neural circuits
Domain
Neuroscience / Neurophysiology / Optogenetics / Two-photon microscopy
Deliverable
physical/clinical work
Required skills
whole-cell patch-clamp electrophysiology, in vivo two-photon microscopy, neurosurgical procedures, Python/MATLAB data analysis, experimental design, animal welfare compliance
Preferred skills
two-photon-guided targeted whole-cell recordings, chronic mouse neurosurgery, optogenetic experiment design, longitudinal imaging, advanced two-photon microscopy systems, genetically encoded indicators, electrophysiology rig maintenance
Technologies
Python, MATLAB, two-photon microscopy, optogenetic stimulation systems, electrophysiology rigs
Responsibilities
Perform high-quality in vivo whole-cell patch-clamp recordings with two-photon guidance; Design and run in vivo experiments combining imaging and optogenetic stimulation; Perform neurosurgical procedures for in vivo electrophysiology; Lead development and optimization of targeted patching methods; Train and mentor team members in experimental techniques
Seniority
Senior, hands-on IC