Associate Director, Statistical Genetics
Core
Lead the Analytical Genetics function to translate human genetic insights into RNAi therapeutics by defining strategy and advancing methods on large-scale biobank datasets.
Role type
Senior IC statistical genetics leader (Associate Director)
Builds
Scalable analytical frameworks and therapeutic hypotheses for RNAi drug discovery
Domain
Biopharmaceuticals / Statistical Genetics / Genomics
Deliverable
production ML models | research | client delivery
Required skills
Statistical genetics (GWAS, RVAS), team leadership, biobank-scale data analysis, post-GWAS causal inference, multi-omics integration, meta-analysis, variant-to-gene mapping, software proficiency (REGENIE, PLINK, METAL, RAREMETAL, REMETA)
Preferred skills
AI/ML-enabled prioritization, multivariate phenotype analysis
Technologies
REGENIE, PLINK, METAL, RAREMETAL, REMETA
Responsibilities
Lead and grow the Analytical Genetics group; Design and oversee large-scale analyses of genetic variation; Define cross-biobank analysis strategies; Guide post-GWAS interpretation and causal inference; Identify and implement emerging analytical approaches; Develop and mentor scientific talent; Represent Alnylam externally; Evaluate external data partnerships
Seniority
Senior, hands-on IC with management responsibilities