CareerPlan

Sr. Scientist, Protein & Cell Sciences

Metaphore Biotechnologies, Inc.Full-time$126k–$182k2026-11-04 → 2026-11-10

Core

Run and optimize the engine to turn computationally designed antibodies into well-characterized, developable therapeutic proteins via protein expression, purification, and analytical characterization.

Role type

Senior Scientist (Protein & Cell Sciences)

Builds

Therapeutic protein candidates (functional antibodies)

Domain

Biotechnology / Protein Biochemistry / Antibody Development

Required skills

mammalian cell culture, protein purification (FPLC), analytical characterization (UHPLC), biophysical methods (BLI, SPR, DSF, DLS), experimental design, troubleshooting, mentorship

Preferred skills

antibody discovery workflows, automated multi-step purification, linear DNA templates, bi/multi-specific antibody formats, team management

Technologies

FPLC, UHPLC, BLI, SPR, DSF, DLS

Responsibilities

Design and execute recombinant protein production workflows; Contribute to experiment design and troubleshooting to improve throughput; Partner with cross-functional teams (Discovery, Engineering, Computational Biology); Mentor junior team members; Establish documentation practices and experimental rigor; Prepare study reports and present results; Support continuous improvement of lab operations

Seniority

Senior, hands-on IC with mentorship