CareerPlan

Principal Data Engineer

Vesalius TherapeuticsFull-time$179k–$236k2026-10-28 → 2026-11-10

Core

Architect and evolve the data platform supporting human genetics, multi-omics, and high-content imaging programs to enable causal biology discovery and therapy identification.

Role type

Principal Data Engineer (Scientific Data Infrastructure)

Builds

AWS-based data lake, orchestration pipelines, metadata catalog, and access layers for scientific datasets.

Domain

Biotechnology / Genomics / Scientific Data Engineering

Deliverable

production ML models

Required skills

AWS architecture, Python, SQL, Infrastructure as Code, CI/CD, Workflow Orchestration, Data Modeling, Cost Governance, Scientific Data Semantics

Preferred skills

Genetics/Genomics data, Microscopy/High-content screening, Databricks, Snowflake, ML infrastructure, LLM/Agent data serving

Technologies

AWS (S3, IAM, EC2, Batch, Lambda, Spark, SageMaker), Nextflow, Airflow, Temporal, CloudFormation/CDK, Databricks, Snowflake, MLflow, Weights & Biases

Responsibilities

Architect AWS environment (account structure, IAM, networking, compute, storage); Lead cost governance (budgets, tagging, rightsizing, lifecycle); Own developer operations (IaC, CI/CD, containers, secrets); Upgrade data lake and ingestion workflows; Partner with ML and computational biology leaders to define platform interfaces.

Seniority

Principal, hands-on IC with architectural leadership