Meridial – Scientist – In Vivo Neuroscience
Core
Establishing and running advanced in vivo neuroscience experiments to map functional neural circuitry in preclinical models for translational drug development.
Role type
Senior hands-on IC experimental scientist (in vivo neuroscience)
Builds
Longitudinal synapse-resolution mapping of functional neural circuitry in mice
Domain
Neuroscience / Preclinical research / Drug development
Deliverable
physical/clinical work
Required skills
Complex survival neurosurgery, two-photon microscopy, optogenetics, animal colony management, experimental protocol development, Python/MATLAB, neural data analysis
Preferred skills
Longitudinal imaging of subcellular structures, all-optical circuit interrogation, viral-vector strategies, intracellular electrophysiology, spatial transcriptomics, head-fixed behavioural experiments
Technologies
Two-photon microscopes, GRIN-lenses, cranial-windows, stereotaxic frames, optogenetic systems, Python, MATLAB
Responsibilities
Perform complex survival neurosurgery and cranial-window preparations; execute longitudinal two-photon imaging and optogenetic experiments; oversee animal colony management and welfare; develop and optimize experimental protocols and SOPs; mentor other scientists; collaborate with engineering and computational teams on system integration and data analysis.
Seniority
Senior, hands-on IC