Director, Pharmacology
Core
Sr. Director leading preclinical pharmacology strategy to translate in vitro biology and functional assay data into meaningful in vivo outcomes for inflammation and hematology programs.
Role type
Sr. Director, Pharmacology (Preclinical R&D)
Builds
Preclinical drug discovery programs from early discovery through candidate selection
Domain
Biotechnology / Pharmacology / Drug Discovery
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Preclinical pharmacology strategy, in vitro to in vivo translation, PK/PD interpretation, exposure-response assessment, translational biomarker strategy, CRO management, data integration, scientific judgment
Preferred skills
Hematology experience, oncology experience, inflammation or immunology program experience, publication record in pharmacology/translational biology, experience in cross-functional biotech environments
Technologies
N/A
Responsibilities
Lead preclinical pharmacology strategy across multiple discovery programs; Drive PK/PD interpretation and translational biomarker strategy; Integrate data across biology, chemistry, and DMPK to guide candidate advancement; Oversee outsourced pharmacology studies and manage external CRO relationships; Partner with internal teams to define critical experiments and interpret data packages; Provide strategic input to cross-functional program discussions; Represent pharmacology at internal meetings to communicate findings and risks
Seniority
Senior, hands-on IC with strategic leadership
