Scientist, Assay Development (Contractor)
Core
Develop, optimize, and validate cell-based and biochemical assays for deployment on automated high-throughput screening platforms to enable the construction of Maps of Biology.
Role type
Senior IC assay development scientist (contractor)
Builds
Robust, transferable assays for high-throughput screening platforms generating petabytes of high-dimensional data from human cells.
Domain
Biotech / Drug discovery / Automation
Deliverable
production ML models
Required skills
Cell-based assay development, biochemical assay optimization, mammalian cell culture, aseptic technique, molecular biology techniques (transfection, nucleic acid/protein handling), plate-based readouts, automated laboratory instrumentation (liquid handlers, plate readers, imagers), experimental design, data analysis, protocol documentation.
Preferred skills
Assay qualification concepts, statistical quality metrics (Z', signal-to-background, CV), computational data analysis (Python, R), genetic perturbation (CRISPR, RNAi), omics readouts (transcriptomics, proteomics), primary or iPSC-derived cell models.
Responsibilities
Develop and optimize assays for automated platforms, execute workflows at scale monitoring quality metrics, analyze experimental data to validate processes and troubleshoot systems, document methods and results for reliable transfer.
Seniority
Senior, hands-on IC
