Scientist I - ADME Tox
Core
Develop and validate LC-MS methods for ADME/DMPK and BioAnalysis applications in a contract research setting.
Role type
Scientist I, analytical chemistry (LC-MS)
Builds
Bioanalytical methods and data for drug metabolism and metabolite identification
Domain
Life sciences / Contract Research Organization (CRO)
Required skills
LC-MS method development, Bioanalytical method validation, Troubleshooting Mass Spectrometers, HPLC operation, Regulatory guideline compliance (FDA/ICH/OECD), Quality Management Systems, Inventory management, Process improvement
Preferred skills
High-Throughput analytical method development, Human mammalian cell culture, Light-based readers (384-well/96-well), Sciex or Thermo High Resolution instrumentation
Technologies
LC-MS, HPLC, Mass Spectrometers, Light-based readers
Responsibilities
Develop LC-MS methods for ADME/DMPK, Perform troubleshooting and maintenance of MS and HPLC units, Prepare and manage inventory of buffers and reagents, Perform data and report QC review, Support validation of new methods, Provide leadership and mentorship for junior scientists
Seniority
Individual Contributor, 1-3 years experience
