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Principal Data Engineer (we have office locations in Cambridge, Leeds and London)

London, England, gb💼 Full-time💰 $103,500–$103,500🗓 2026-09-28 → 2026-10-01

Core

Senior technical leadership for enterprise-scale data platforms handling sensitive clinical and genomic data, focusing on architecture, security, and sustainable engineering practices.

Role type

Principal individual contributor data engineer

Builds

Secure, resilient, and scalable data platforms, pipelines, and data products for clinical and research use

Domain

Healthcare, Genomics, Research

Deliverable

production ML models

Required skills

Enterprise-scale data platform design, Cloud infrastructure, Scalable data storage and processing, Hands-on programming, Data modelling, Data lifecycle management, Security and governance, CI/CD and automation, Technical leadership and mentoring

Preferred skills

Genomic/bioinformatics data formats (VCF, BAM, FASTQ), Standards (GA4GH, OMOP, FHIR), Orchestration (Airflow, Prefect, AWS Glue), Lakehouse/Data mesh, Secure Data Environments, Scala/Java/Shell

Technologies

Cloud, Lakehouse, Distributed systems, Event-driven systems, Airflow, Prefect, AWS Glue, Scala, Java, Shell/Bash

Responsibilities

Shape strategic and technical direction for data engineering, Set standards for secure and scalable data platforms, Lead hands-on design and delivery of complex data solutions, Provide architectural guidance for distributed and event-driven systems, Collaborate across engineering, bioinformatics, and product teams, Mentor engineers and strengthen engineering practices

Seniority

Principal, hands-on IC with strategic influence

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