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Principal Data Engineer (we have office locations in Cambridge, Leeds and London)

London, England, gb💼 Full-time💰 $103,500–$103,500🗓 2026-09-25

Core

Senior technical leadership for data engineering capability, shaping strategic direction, architectural guidance, and hands-on delivery of secure, scalable platforms for clinical and research genomic data.

Role type

Principal individual contributor data engineer

Builds

Secure, resilient, and scalable data platforms, pipelines, and data products for national-scale clinical and research use.

Domain

Healthcare / Genomics / Data Engineering

Deliverable

production ML models | product features | infrastructure

Required skills

Data engineering, cloud infrastructure, scalable data storage and processing, data modelling, data lifecycle management, metadata and provenance, privacy and security, CI/CD, infrastructure as code, automation, observability, mentoring, technical leadership

Preferred skills

Genomic/bioinformatics/clinical data platforms, GA4GH/OMOP/FHIR standards, orchestration (Airflow/Prefect/AWS Glue), Lakehouse/data mesh, distributed/event-driven architectures, Scala/Java/Shell

Technologies

Cloud, Lakehouse, distributed systems, event-driven systems, Airflow, Prefect, AWS Glue, Scala, Java, Shell/Bash

Responsibilities

Provide technical leadership and shape strategic/technical direction; set standards for secure, scalable platforms; lead hands-on design and delivery of complex data solutions; provide architectural guidance on Lakehouse and distributed systems; collaborate across engineering, bioinformatics, and governance; embed privacy, security, and regulatory requirements; strengthen engineering practices via DataOps/DevOps; evaluate emerging technologies; mentor experienced engineers.

Seniority

Principal, hands-on IC with strategic influence

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