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LCMS Scientist

Saint Charles, MO, us💼 Full-time🗓 2026-09-22 → 2026-09-26

Core

Develops and validates LC-MS methods for ADME/DMPK applications in a contract research setting, supporting production assays and new service line expansion.

Role type

Senior IC analytical chemist (LC-MS methods development)

Builds

Production assays for ADME Toxicology Services and supporting services (BioMAP, Immunosignaling, Ion Channel, OncoPanel)

Domain

Life sciences / Contract Research Organization (CRO) / Drug Discovery

Deliverable

production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work

Required skills

LC-MS method development, ADME/DMPK quantification, analytical method validation, troubleshooting mass spectrometers/HPLC, GxP compliance, data QC review, inventory management, small team leadership

Preferred skills

Sciex or Waters instrumentation experience, liquid handling/automation/SPE/HTS, statistical analysis, cross-functional project support

Technologies

LC-MS, HPLC, Sciex, Waters, GxP systems

Responsibilities

Develop LC-MS methods for ADME/DMPK, troubleshoot and maintain MS/HPLC units, manage reagent inventory, perform data QC review, support method validation, lead small projects with minimal supervision, train colleagues

Seniority

Senior, hands-on IC with project leadership

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