Downstream Process Development Engineer
Core
Perform lab-scale downstream processing and biochemical/analytical assays for vaccine adjuvant and Lipid Nanoparticle (LNP) products and intermediates.
Role type
Senior IC process development engineer (biopharmaceuticals)
Builds
Lab-scale process unit operations for vaccine adjuvants and LNPs
Domain
Biopharmaceuticals / Vaccine manufacturing
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Lab-scale downstream processing, biochemical/analytical assays, solution preparation, GMP compliance, potent compound lipid handling (OEB4 & 5), isolator/VBE operation, Extrusion, Tee-mixing, Multi-Inlet-Vortex-Mixing (MIVM), Homogenization/Microfluidization, Filtration, Tangential Flow Filtration (TFF), scale-up experience
Preferred skills
Experience with liposome and LNP formation unit ops
Technologies
Extrusion, Tee-mixing, MIVM, Homogenization, Microfluidization, Filtration, TFF, Isolators, VBEs
Responsibilities
Perform lab-scale downstream processing of vaccine adjuvant & LNP products, perform assays on products and intermediates, prepare solutions/reagents, set-up process equipment for lab-scale experiments, maintain records and experimental results following GMP
Seniority
Senior, hands-on IC