Oligonucleotide Senior Scientist
Core
Develop, optimize, and scale chemical synthesis and purification processes for high-throughput oligonucleotide production.
Role type
Senior IC organic chemist (oligonucleotide process development)
Builds
High-quality oligonucleotides for manufacturing
Domain
Life sciences / Genomics / Pharmaceutical manufacturing
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
solid-phase oligonucleotide synthesis, oligonucleotide purification (HPLC, ion-exchange), process scale-up, analytical methods (HPLC, LC-MS), GMP compliance, SOP authoring
Preferred skills
automated DNA/RNA synthesizers, modified nucleotides, high-throughput oligo production
Technologies
HPLC, LC-MS, automated DNA/RNA synthesizers
Responsibilities
Design and optimize chemical synthesis processes, troubleshoot synthesis and purification challenges, collaborate on process transfer, evaluate new chemistries and technologies, author technical documentation, mentor lab technicians
Seniority
Senior, hands-on IC