LC-MS/MS Sr. Scientist
Core
Develops and validates LC-MS/MS methods for ADME/DMPK applications in biological matrices, performing production assays and troubleshooting mass spectrometry equipment.
Role type
Senior Individual Contributor Analytical Scientist (LC-MS/MS)
Builds
Production assays and analytical methods for ADME Toxicology Services
Domain
Life Sciences / Contract Research Organization (CRO) / Drug Discovery
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
LC-MS/MS method development, ADME/DMPK quantification, mass spectrometry troubleshooting, HPLC operation, bioanalytical method validation, regulatory compliance (FDA/ICH), small team leadership, project management
Preferred skills
Sciex or Waters instrumentation experience, liquid handling automation, solid-phase extraction (SPE), HTS applications, statistical analysis
Technologies
LC-MS, HPLC, Sciex, Waters
Responsibilities
Develop LC-MS methods for ADME/DMPK, troubleshoot and maintain mass spectrometers and HPLC units, prepare and manage inventory of buffers and reagents, perform data and report QC review, support validation of new methods, lead small projects with minimal supervision, train colleagues and external users
Seniority
Senior, hands-on IC with project leadership