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Particle Engineering Scientist

Macclesfield, England, gb💼 Full-time🗓 2026-08-03 → 2026-09-26

Core

Provide crystallization support for the development and delivery of intermediates and API particle processes, defining desired particle properties for formulations, manufacturability, and bioavailability.

Role type

Senior IC particle engineering scientist (pharmaceuticals)

Builds

Drug substance intermediates and APIs with controlled solid forms

Domain

Pharmaceutical manufacturing / Particle engineering

Deliverable

production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work

Required skills

Crystallization development, Polymorphism control, Solid-form control, Nucleation and crystal growth mechanisms, Scale-up of crystallization processes, Design of Experiments (DoE), API physical attributes analysis, Process robustness studies, Optical and electron microscopy (SEM), X-ray powder diffraction (XRPD), Differential scanning calorimetry (DSC), Thermogravimetric analysis (TGA), Inline Process Analytical Technology (PAT)

Preferred skills

Scale-up from laboratory to pilot plant and commercial manufacture, Process robustness studies using DoE

Technologies

SEM, XRPD, DSC, TGA, PAT

Responsibilities

Contribute to sustainable process development projects for drug substances, Collaborate with Drug Product Development teams to define particle properties, Generate and interpret high-quality data for development projects, Ensure work complies with GMP, Safety, Health & Environment standards

Seniority

Senior, hands-on IC

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