Senior Scientist, Materials Development
Core
Design advanced solid form screening approaches, amorphous solid dispersion (ASD) formulations, and predictive mathematical models for beyond Rule-of-5 (bRo5) molecules including PROTACs, RIPTACs, and molecular glues.
Role type
Senior Scientist, Materials Development (Pharmaceutical Solid State)
Builds
Solid form screening strategies and ASD formulations for clinical studies
Domain
Pharmaceutical solid-state chemistry and formulation
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Solid-state characterization, crystallization techniques, amorphous solid dispersion strategies, mathematical modeling, infrared spectroscopy (FTIR, NIR, FT-Raman), SSNMR, particle characterization
Preferred skills
Experience with large bRo5 molecules, multidisciplinary collaboration
Technologies
x-ray powder diffraction, polarized light microscopy, differential scanning calorimetry, thermogravimetric analysis, spectroscopy
Responsibilities
Conduct advanced solid-state characterization of large bRo5 molecules, apply novel crystallization techniques to recrystallize bRo5 molecules, collaborate with colleagues to define and implement crystallization, polymorph, salt, and co-crystal screening activities, solve scientific problems using contemporary Materials Science experimental techniques, contribute to the development of new scientific approaches and knowledge within the Materials Science organization
Seniority
Senior, hands-on IC
