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Staff / Principal Software Engineer

Palo Alto, CA💼 Full-time🗓 2026-08-18 → 2026-09-26

Core

Build the user-facing platform and backend services for the Virtual Cell World Model, a multimodal AI system that simulates and programs cellular behavior for drug discovery.

Role type

Staff / Principal Software Engineer (Senior IC)

Builds

Production-grade backend services, APIs, and scalable systems for biological simulations and AI inference.

Domain

Computational biology / AI-driven drug discovery

Deliverable

production ML models | product features | infrastructure

Required skills

Clean architecture, modular system design, distributed backend systems, AI/LLM inference integration, scalable API design, performance optimization, cross-functional leadership

Preferred skills

Computational biology domain knowledge, scientific simulation tools, automated experiment management, workflow orchestration, AI-native framework development

Technologies

None explicitly stated

Responsibilities

Build production-grade backend services and APIs for Virtual Cell products; Design interfaces connecting frontend, business logic, databases, and AI engines; Architect scalable systems for biological simulations and data processing; Optimize platform performance via caching and distributed infrastructure; Collaborate with AI researchers to translate models into scientific products; Work cross-functionally to deliver computational experiences for scientists.

Seniority

Staff / Principal, hands-on IC with technical leadership

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